Autism & Pervasive Developmental Disorder


What is Autism & Pervasive Developmental Disorders?

These disorders start in infancy or early childhood. Children with these disorders have speech and language deficits cognitive impairments and impairments in their ability to relate to others which tend to persist throughout life. These disorders are severe and are often present with other disorders. The most common accompanying or comorbid disorders are mental retardation and epilepsy. Boys are affected more frequently than girls (3 to 1). Children with these disorders will usually require life long treatment and assistance.

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  • Peng, C., Hatlestad, P., Klug, M.G., Kerbeshian, J., & Burd, L Health Care Costs and Utilization Rates for Children with Pervasive Developmental Disorders in North Dakota From 1998 to 2004: Impact on Medicaid.Journal of Child Neurology.2009. 24(2): 140-147.

  • Kerbeshian, J., Burd, L., & Tait, A. Chain Reaction or Time Bomb: A Neuropsychiatric-Developmental/Neurodevelopmental Formulation of Tourettisms, Pervasive Developmental Disorder, and Schizophreniform Symptomatology Associated with PANDAS.World Journal of Biological Psychiatry.2007. 8(3): 201-207.

  • Kerbeshian, J. & Burd, L. Letter to the Editor: Tourette Syndrome and Prognosis in Autism.European Child and Adolescent Psychiatry.2003. 12(2): 103.

  • Klug, M.G., Burd, L., Kerbeshian, J., Benz, B., & Martsolf, J.T. A Comparison of the Effects of Parental Risk Markers on Pre- and Perinatal Variables in Multiple Patient Cohorts with Fetal Alcohol Syndrome, Autism, Tourette Syndrome, and Sudden Infant Death Syndrome: An Enviromic Analysis.Neurotoxicology and Teratology.2003. 25(6): 707-717.

  • Burd, L., Kerbeshian, J., Westerland, A., LaBine, J., Barth, A., Klug, M.G., & Wagner, K.J. Prospective Long-Term Follow-Up of Patients with Pervasive Developmental Disorders.Journal of Child Neurology .2002. 17(9): 681-688.

  • Kerbeshian, J., Burd, L., & Avery, K. Pharmacotherapy of Autism: A Review and Clinical Approach.Journal of Developmental and Physical Disabilities.2001. 13(3): 199-227.

  • Burd, L., Stenehjem, A., Franceschini, L., & Kerbeshian, J. A Fifteen Year Follow-Up of a Boy with Pyridoxine (Vitamin B6) Dependent Seizures with Autism, Breath Holding, and Severe Mental Retardation.Journal of Child Neurology.2000. 15(11): 763-765.

  • Kerbeshian, J. & Burd, L. Peek-A-Boo Fragile Site? Or a Peek-A-Boo Paper?American Journal of Medical Genetics.2000. 96(3): 430-431.

  • Kerbeshian, J., Severud, R., Burd, L., & Larson, L. Peek-A-Boo Fragile Site at 16D Associated with Tourette Syndrome, Bipolar Disorder, Autistic Disorder, and Mental Retardation.American Journal of Medical Genetics.2000. 96(1): 69-73.

  • Burd, L., Severud, R., Kerbeshian, J., & Klug, M. Prenatal and Perinatal Risk Factors for Autism.Journal of Perinatal Medicine.1999. 27(6): 441-450.

  • Burd, L., Ivey, M., Barth, A., & Kerbeshian, J. Two Males With Childhood Disintegrative Disorder: A Prospective 14-Year Outcome Study.Developmental Medicine and Child Neurology.1998. 40: 702-707.

  • Kerbeshian, J. & Burd, L. Case Study: Comorbidity Among Tourette’s Syndrome, Autistic Disorder and Bipolar Disorder.Journal of the American Academy of Child and Adolescent Psychiatry.1996. 35(5): 681-685.

  • Kerbeshian, J. & Burd, L. A Clinical Pharmacological Approach to the Treatment of Autism.The Habilitative Mental Health Care Newsletter.1991. 10(6): 33-36.

  • Kerbeshian, J., Burd, L., & Fisher W. Asperger's Syndrome: To Be or Not to Be?The British Journal of Psychiatry.1990. 156: 721-725.

  • Kerbeshian, J., Burd, L., Randall, T., Martsolf, J.T., & Jalal S. Autism, Profound Mental Retardation, and Atypical Bipolar Disorder in a 33-Year-Old Female With a Deletion of 15q12.Journal of Mental Deficiency Research.1990. 34: 205-210.

  • Burd, L. Research on Autism and Other Pervasive Developmental Disorders.Developmental Disabilities Network News .1989. 3(1): 10-12.

  • Burd, L., Fisher, W., & Kerbeshian J. Pervasive Disintegrative Disorder: Are Rett Syndrome and Heller Dementia Infantalis Subtypes?Developmental Medicine and Child Neurology.1989. 31: 609-616.

  • Burd, L. & Kerbeshian J. Case Study: Psychogenic and Neurodevelopmental Factors in Autism.Journal of the American Academy of Child and Adolescent Psychiatry .1988. 27: 252-253.

  • Burd, L. & Kerbeshian J. Familial Pervasive Development Disorder, Tourette Disorder and Hyperlexia.Neuroscience and Bio¬behavioral Reviews.1988. 12: 233-234.

  • Burd, L. & Kerbeshian J. Diagnosis of Autism and Other Pervasive Developmental Disorders.Neuroscience and Biobehavioral Reviews.1988. 12: 275-282.

  • Burd, L., Fisher, W., & Kerbeshian J. Childhood Onset jPervasive Development Disorder.Journal of Child Psychology, Psychiatry and Allied Disciplines.1988. 29(2): 155-163.

  • Burd, L., Fisher, W., Kerbeshian, J., Vesely, B., Durgin, B., & Reep P. A Comparison of Breastfeeding Rates Among Children with Pervasive Developmental Disorder and Controls.Journal of Developmental and Behavioral Pediatrics.1988. 9(5): 247-251.

  • Burd, L., Martsolf, J.T., Kerbeshian, J., & Jalal S.M. Partial 6p Trisomy Associated with Infantile Autism.Clinical Genetics.1988. 33: 356-359.

  • Fisher, W., Burd, L., & Kerbeshian J. Markers for Improvement in Children with Pervasive Developmental Disorders.Journal of Mental Deficiency Research.1988. 32: 357-364.

  • Burd, L. The Fragile X Chromosome.The New England Journal of Medicine.1987. 316: 483.

  • Burd, L., Fisher, W., & Kerbeshian J. A Prevalence Study of Pervasive Developmental Disorders in North Dakota.Journal of the American Academy of Child and Adolescent Psychiatry.1987. 26: 700-703.

  • Burd, L., Fisher, W., Kerbeshian, J., & Arnold M.E. Is Development of Tourette Disorder a Marker for Improvement in Patients with Autism and Other Pervasive Developmental Disorders?Journal of the American Academy of Child and Adolescent Psychiatry.1987. 26: 162-165.

  • Burd, L., Fisher, W., Knowlton, D., & Kerbeshian J. Hyperlexia: A Marker for Improvement in Children with Pervasive Developmental Disorders?Journal of the American Academy of Child and Adolescent Psychiatry.1987. 26: 407-412.

  • Fisher, W., Burd, L., & Kerbeshian J. Comparisons of DSM-III Defined Pervasive Developmental Disorders in North Dakota Children.Journal of the American Academy of Child and Adolescent Psychiatry.1987. 26: 704-710.

  • Kerbeshian, J., Burd, L., & Fisher W. Lithium Carbonate in the Treatment of Two Patients with Infantile Autism and Atypical Bipolar Symptomatology.Journal of Clinical Psychopharmacology.1987. 7(6): 401-405.

  • Burd, L. Bornhoeft, D.M., & Kerbeshian J. Fragile X Syndrome: Developmental Aspects.Child Study Journal.1986. 16(4): 285-296.

  • Fisher, W., Kerbeshian, J., & Burd L. A Treatable Language Disorder: Pharmacological Treatment of Pervasive Developmental Disorder.Journal of Developmental and Behavioral Pediatrics.1986. 7(2): 73-76.

  • Fisher, W., Kerbeshian, J., Burd, L. & Kolstoe, P. Tuberous Sclerosis and Autism.Developmental Medicine and Child Neurology .1986. 28: 814-815.

  • Kerbeshian, J. & Burd L. Asperger's Syndrome and Tourette Syndrome: The Case of the Pinball Wizard.British Journal of Psychiatry.1986. 148: 731-736.

  • Kerbeshian, J. & Burd L. A Second Visually Impaired, Mentally Retarded Male With Pervasive Developmental Disorder, Tourette Disorder and Ganser’s Syndrome: Diagnostic Classification and Treatment.Interna¬tional Journal of Psychiatry in Medicine.1986. 16(1): 67-75.

  • Burd, L. & Kerbeshian J. Tourette Syndrome, Atypical Pervasive Developmental Disorder, and Ganser Syndrome in a 15-year-old, Visually Impaired, Mentally Retarded Boy.Canadian Journal of Psychiatry.1985. 30(1): 74-76.

  • Burd, L., Fisher, W., & Kerbeshian J. Pervasive Developmental Disorders in Multiply Disabled Children.Rehabilitation Literature.1985. 46(9-10): 246-249.

  • Burd, L., Kerbeshian, J., & Fisher W Inquiry into the Incidence of Hyperlexia in a Statewide Population of Children with Pervasive Developmental Disorder.Psychological Reports.1985. 57: 236-238.

  • Burd, L., Kerbeshian, J., Fisher, W., & Martsolf, J.T. A Case of Autism and Mosaic of Trisomy 8.Journal of Autism and Developmental Disorders.1985. 15: 351-352.

  • Kerbeshian, J. & Burd L. Auditory Hallucinosis and Atypical Tic Disorder: Case Reports.Journal of Clinical Psychiatry.1985. 46(9): 189-197.

  • Kerbeshian, J., Burd, L. & Martsolf, J. The Multipotential Outcome of Fragile X Syndrome.Journal of Developmental and Behavioral Pediatrics.1985. 6: 322.

  • Kerbeshian, J., Burd, L., & Martsolf J. Fragile X Syndrome Associated with Tourette Symptomatology in A Male with Moderate Mental Retardation and Autism.Journal of Developmental Behavioral Pediatrics .1984. 5(4): 201-203.

  • Kerbeshian, J., Burd, L., & Martsolf J. A Family with Fragile X Syndrome.The Journal of Nervous and Mental Disease.1984. 172(9): 549-551.